nginx error - ssl handshaking and timeout errors

[worldkryptonite]

Hi Team,

I have been searching for a solution for the below problem appearing in the logs.

I have a flask setup and I am calling the api from another domain using javascript.
Very often, I get the below error and I wanted to know if there is a known cause and solution:

 

Please let me know if you need more information.

Thanks and regards,

Yashveen